http://www.ivypub.org/journal/RSS.aspx?J=BF&lang=cnen-US2022-0<p class="abstract">General Review of New Plant Cell Culture Equipment</p><ul><li>Pages 1-7</li><li>Author Haoyu A</li><li>Abstract Research and development of plant cell culture equipment is a hot spot in the field of plant cell culture. On the basis of the introduction of plant cell culture universal problems, various types of plant cell culture bioreactor of the structure, principle, advantages and disadvantages and derived new cultivation equipment are introduced and comparatively analyzed. Besides, this review provides reference to the selection and improvement of plant cell culture bioreactor, and puts forward the future prospect of plant cell culture.</li></ul>/BF/paperinfo/56771.shtmlBiotechnology Frontier/BF/paperinfo/56771.shtml2022-0<p class="abstract">Magnetic Resonance Tumor Image Segmentation Method Based on Multimodal Hierarchical Fusion</p><ul><li>Pages 8-16</li><li>Author Rong ChenZhan GaoYeqin ShaoChangyan X</li><li>Abstract Aiming at the problems of sensor noise and slow volume rendering in magnetic resonance images, an improved ray-casting algorithm is proposed to visualize the breast and lesion in Magnetic Resonance Imaging (MRI). First, a linear minimum mean square error (LMMSE) filter is used to denoise the breast magnetic resonance images. Then, in order to improve the algorithm of volume rendering, the ray casting algorithm is improved by using bilinear interpolation operation and ray early termination technology. Finally, the three-dimensional visualization of the breast MRI images is realized based on VTK library. Experiments show that the proposed method can improve the rendering speed of breast MRI images while ensuring image quality, and assist doctors to understand the internal situation of the breast and the condition of the lesions intuitively.</li></ul>/BF/paperinfo/56772.shtmlBiotechnology Frontier/BF/paperinfo/56772.shtml2022-0<p class="abstract">Observation of Medical Anthropology on Covid-19 Variants Epidemic Prevention</p><ul><li>Pages 17-23</li><li>Author Weijian XiBei WangLiangfu L</li><li>Abstract In recent years, the thinking and research on the prevention and control of Covid-19 Variants Epidemic is not only the technical operation level discussion in the public health and disease prevention academic circles, there is also growing academic interest in comparative research on public health governance and different paradigms. Based on the experience of Shenzhen's epidemic prevention and control team at the community governance level in 2022, based on the observational perspective of medical anthropology, and through comparison with Hong Kong's anti-epidemic experience, this paper deeply analyzes the function and impact of traditional medical methods in epidemic prevention and control. Then the authors cite the paradigm of ‘systems medicine’ and research results in recent years, closely link the research topic with community governance in methodological sense, so as to promote public health and epidemic prevention research that aim at the combination of technology and humanities.</li></ul>/BF/paperinfo/56773.shtmlBiotechnology Frontier/BF/paperinfo/56773.shtml2022-0<p class="abstract">Construction and Research of Sports Medicine Environment in Sports Experimental Center</p><ul><li>Pages 24-28</li><li>Author Gongyan Zha</li><li>Abstract In the education system of colleges and universities, experimental teaching is an important part. In order to ensure the smooth development of teaching and scientific research and promote the long-term sustainable development of the laboratory, it’s important to realize the preservation and standardized management of experimental products required for sports medical research (sports human body science laboratory). This paper summarizes the problems existing in the laboratory management of physical education colleges in colleges and universities, and puts forward corresponding improvement measures.</li></ul>/BF/paperinfo/56813.shtmlBiotechnology Frontier/BF/paperinfo/56813.shtml2022-0<p class="abstract">Effect of Biofeedback Training on Female Drug Addicts with Hypertension</p><ul><li>Pages 29-33</li><li>Author Wen ZhouGuocai L</li><li>Abstract Objective: This study aims to analyze and study the treatment effects of different treatment methods for female drug addicts with hypertension, and to provide specific treatment methods according to the characteristics of the group. Methods: 60 female patients with drug abuse and hypertension treated from January 2019 to January 2020 were randomly divided into two groups. The control group was treated with conventional antihypertensive drugs, and the experimental group was treated in combination with biofeedback training on the basis of the control group. The effects of different treatment methods on the control of blood pressure, blood lipid, and blood glucose of the two groups were compared, and the adverse reactions of the two groups were recorded. Results: There was no significant difference in diastolic and systolic blood pressure between the two groups before treatment (P > 0.05). After 6 weeks of treatment, the diastolic and systolic blood pressure in the experimental group were significantly lower than those in the control group (P < 0.05). After treatment, the decreasing trend of diastolic and systolic blood pressure in the experimental group was significantly higher than that in the control group. The blood lipid indexes of the two groups decreased significantly after treatment compared with that before treatment, and the indexes of the experimental group were significantly lower than those of the control group (P < 0.05). During the treatment, the incidence of adverse reactions in the experimental group was 10%, while that in the control group was 6%, showing the difference was not statistically significant (P > 0.05). Conclusion: The combination of routine medication with biofeedback training can effectively control the blood pressure of female drug addicts with hypertension, and can reduce the level of blood glucose and blood lipid, which is safe and worthy of clinical application.</li></ul>/BF/paperinfo/56814.shtmlBiotechnology Frontier/BF/paperinfo/56814.shtml2022-0<p class="abstract">Expression of MiR-133a-3p in Bladder Cancer and its Molecular Mechanism</p><ul><li>Pages 34-41</li><li>Author Jialin LiuGaoqiang ZhaiZhiguang HuangZengnan MoJiwen ChengShenghua L</li><li>Abstract Objective: Using bioinformatics techniques, it is our goal to investigate miR-133a-3p expression in bladder cancer tissues and its clinical relevance, as well as to pinpoint its target genes and signaling pathways. Methods: The expression level and clinical value of miR-133a-3p were assessed using 514 bladder cancer tissue samples and 78 non-cancer tissue samples from various public high-throughput databases. The signaling pathways associated with the progression of bladder cancer and hub genes were found using the miR-133a-3p target genes, and this further confirmed the association between hub genes and miR-133a-3p. Results: In bladder cancer tissues compared to non-cancerous tissues, miR-133a-3p expression was significantly downregulated (SMD=-1.604, p=0.015), and it was significant for diagnosing bladder cancer (AUC=0.910, 95%CI: 0.880 to 0.930), bladder cancer patients with high expression of miR-133a-3p had a relatively poor prognosis (HR=1.383, p=0.030). Different age at disease (t=2.414, p=0.0162), disease stage (T stage: t=2.488, p=0.0133; N stage: t=3.153, p=0.0017), pathological grade (t=2.067, p= 0.0393) and tumor subtypes (t=3.118, p=0.0048), the expression levels of miR-133a-3p were significantly different. The pathway results demonstrated that miR-133a-3p target genes were functionally enriched in the pathways of “cancer cell apoptosis,” “cadherin-bound cell adhesion” and “cytoskeleton formation.” Protein interaction network was used to screen a total of 9 hub genes (EGFR, CLTA, ARPC5, TFRC, NUDT21, FPR3, LAMC1, GNAI3, CAP1), of which CLTA, TFRC, NUDT21, and CAP1 had significantly negative correlations with miR-133a-3p. Conclusion: MiR-133a-3p, a reliable marker and prognostic factor for the disease, is downregulated in bladder cancer. It can affect the progression of bladder cancer through various signaling pathways.</li></ul>/BF/paperinfo/58099.shtmlBiotechnology Frontier/BF/paperinfo/58099.shtml2022-0<p class="abstract">Research on Compliance Management of Medical Institutions on Frozen Embryos</p><ul><li>Pages 42-45</li><li>Author Xinyue Zhan</li><li>Abstract The compliance management of medical institutions on frozen embryos has shortcomings in management concept, management behavior and risk aversion. Under the background of the increasing application of artificial assisted reproduction technology, the loopholes in compliance management will inevitably bring unnecessary disputes to medical institutions, and even create administrative liability risks and legal liability risks. At present, there is a big gap between medical institutions' compliance management expectation and litigation practice, and there is a contradiction between their compliance management concept and judicial attitude. Perhaps medical institutions should change their focus, start from the medical service contract itself, conduct compliance management from the source, improve the contract content, and build a multi-level informed consent system. Finally, introduce the power of judicial procedure to reduce the legal risk and administrative responsibility risk.</li></ul>/BF/paperinfo/58166.shtmlBiotechnology Frontier/BF/paperinfo/58166.shtml2022-0<p class="abstract">Clinical Study on the Treatment of Unstable Angina Pectoris with Compound Danshen Dropping Pill and Auricular Points Plaster Therapy</p><ul><li>Pages 46-50</li><li>Author Shengfei Li</li><li>Abstract Objective: To observe the clinical efficacy of Compound Danshen Dropping Pill combined with auricular points plaster therapy in the treatment of unstable angina pectoris. Methods: 121 patients were randomly divided into the study group and the control group by single-blind method. The study group was mainly treated with Compound Danshen Dropping Pill combined with auricular points plaster therapy, and the control group was treated with isosorbide mononitrate tablets. The effects were observed after 4 weeks of treatment. Results: The total effective rate of the study group was 91.80%, which was higher than 81.33% of the control group, with no significant difference (P>0.05); The incidence of adverse reactions in the study group and the control group were 8.20% and 20.00%, respectively, and there was no significant difference between the two groups (P>0.05). Before treatment, the frequency of angina attack in the study group was 7.26 ± 3.30 times/week, and that in the control group was 7.47 ± 3.10 times/week, with no significant difference (P>0.05); After treatment, the frequency of angina pectoris attack in the study group was 3.07 ± 1.30 times/week, and that in the control group was 3.66 ± 0.82 times/week. The comparison before and after treatment in the study group was P<0.05, which was statistically significant. The comparison before and after treatment in the control group was P<0.05, which was statistically significant, indicating that both groups had significant therapeutic effects. Conclusion: The use of Compound Danshen Dropping Pill combined with auricular points plaster therapy has a definite clinical effect on patients with coronary heart disease. It can significantly improve the symptoms of angina pectoris, reduce the frequency of angina pectoris, improve the efficacy, reduce the occurrence of adverse reactions, and have a higher safety.</li></ul>/BF/paperinfo/58314.shtmlBiotechnology Frontier/BF/paperinfo/58314.shtml